Beat the disease
Nutritional clinical trial to cure preeclampsia
Sound crazy to you? You betcha! But we 1) think this will work 2) this is LOW risk, and 3) this is CHEAP, so 4) let's DO IT!
Nutrition 4 New Life: fighting preeclampsia
Dr. Andrea Loewendorf, PhD
Dr. Nancy Hart, MD, FACOG, Member ASBMB, American Physiological Society
Dr. Nancy Hart, MD, FACOG, Member ASBMB, American Physiological Society
ImmunoVENtion
Immunologist
Study protocol
General organization
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Dr. Nancy Hart, MD, FACOG, Member ASBMB, American Physiological Society
Dr. Nancy Hart, MD, FACOG, Member ASBMB, American Physiological Society
Dr. Nancy Hart, MD, FACOG, Member ASBMB, American Physiological Society
OB-Gyn
study protocol
nutritional interventions
medical oversight
data analysis
Dr. Janice Hall PhD
Dr. Janice Hall PhD
Dr. Janice Hall PhD
Biomedical Engineer,
Maternal Beats,
Community Advisory Board - Southern Center for Maternal Health Equity
Sarah Thompson
Dr. Janice Hall PhD
Dr. Janice Hall PhD
Sarah Thompson, Functional Medicine, Acupuncturist, Doula
What does the Nutrition4NewLife trial look like?
Prospective single-arm nutritional interventional trial to remediate symptomatic preeclampsia
we need 17 patients
as low risk as clinical trials can go
preeclampsia nutrition pregnancy nutrition clinical trial preeclampsia
The idea behind the trial
Scientific rationale aka why?
The hypothesis we are testing is:
Preeclampsia is due to malnutrition and can be cured by resolving nutritional deficiencies
A word from Dr. Andrea Loewendorf, Phd:
This is a strong statement and if I didn't know the people behind it, I wouldn't participate in this. Believe me, I am the last person who wants to see another nonsense preeclampsia trial. This is not what this is. Dr. Hart's theory is sound!
Here's a link to the two papers by Dr. Hart that best describe her way of thinking. Enjoy!
Paradoxes: cholesterol and hypoxia in preeclampsia
https://www.mdpi.com/2218-273X/14/6/691
A theoretical model of dietary lipid variance as the origin of primary ciliary dysfunction in preeclampsia
How Can I help?
Clinical Trial Site
You are an OB/Gyn practitioner and are interested in putting an end to pre eclampsia?
You are a doula, a nurse, run a clinic, are a janitor at a clinic that might be interested? Let us know, please! aLoewendorf@gmail.com
Additional Analysis
You want to help with this trial by donating some services? Analyze some cytokines, lipids, siRNA for us? Bring it on, we will advertise the #^#^%$ out of you!!
Statistics help
You are a biostatistician and don't know what to do with yourself on the evenings? Let us know, we can use your help! aLoewendorf@gmail.com
Other ideas?
Please let us know, we welcome most ideas!
What's next?
We cured preeclampsia - but what exactly happened?
Using serum from preeclamptic women from our nutrition4newlife trial, we will collaborate with the Kidambi lab to understand the mechanism.
Cell treatment
For those women that display symptoms even after the nutrition therapy (Dr. Hart will disagree on this point) or can't do the nutrition therapy for some reason, the regulatory T cell therapy will be developed by ImmunoVEntion.
Bring nutrition counseling to everyone!
Our Co-PI Dr. Janice Hall develops an app with her company Maternal Beats bringing the knowledge of Dr. Nancy Hart and Sarah Thompson to as many women as we can possibly reach.